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キムラ　ダイスケ   KIMURA DAISUKE   木村　大輔    所属   健康福祉学部 健康スポーツ栄養学科    職種   教授

■ 現在の専門分野 寄生虫学, 免疫学, 衛生学、公衆衛生学分野：実験系を含む

■ 著書・論文歴 1. 著書　 「飲める米糠」を目指した新規米糠の加工法ならびにその機能性の評価 米の機能性食品化と新規利用技術・高度加工技術の開発  （共著） 2023/05 2. 著書　 別冊BIO Clinica 慢性炎症と疾患   （共著） 2017/04 3. 著書　 IL-27による免疫抑制 臨床免疫・アレルギー科 67(1),23-29頁 （共著） 2017/01 4. 著書　 臨床免疫・アレルギー科   （共著） 2016/12 5. 著書　 臨床免疫・アレルギー科   （共著） 2014/10 6. 著書　 化学療法の領域   （共著） 2014/01 7. 著書　 寄生虫学研究 -材料と方法- （再掲）   （共著） 2012/06 8. 著書　 実験医学増刊号   （共著） 2011/10 9. 著書　 虫の知らせ   （共著） 2002/07 10. 論文　 IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells.  e17713 （共著） 2023/10 11. 論文　 Description and molecular characterisation of Pelecitus copsychi Uni, Mat Udin & Martin n. sp. (Nematoda: Onchocercidae) from the white-rumped shama Copsychus malabaricus (Scopoli) (Passeriformes: Muscicapidae) of Pahang, Malaysia  2,pp.100078 （共著） 2022/01 12. 論文　 Type I interferon production elicits differential CD4+ T-cell responses in mice infected with Plasmodium berghei ANKA and P. chabaudi International Immunology 31(1),pp.21-33 （共著） 2022/01 13. 論文　 CD49d marks Th1 and Tfh-like antigen-specific CD4+ T cells during Plasmodium chabaudi infection International Immunology 33(8),pp.409-422 （共著） 2021/04 14. 論文　 Prevalence of Onchocerca japonica and O. takaokai infections in the Japanese wild boar, Sus scrofa leucomystax, and the Ryukyu wild boar, S. s. riukiuanus, in Japan Parasitology International  （共著） 2021/03 15. 論文　 Activation and IL-10 production of specific CD4+ T cells are regulated by IL-27 during chronic infection with Plasmodium chabaudi. Parasitology International 74 （共著） 2020/02 16. 論文　 Comparative study on the quality and safety aspects of Climbing perch (Anabas testudineus) and Nile tilapia (Oreochromis niloticus) from pond and openwater of Mymensingh, Bangladesh. Bangladesh Journal of Fisheries 31(1),pp.119-124 （共著） 2019/08 17. 論文　 Use of Pesticide, Harmful Chemicals, Antibiotic During Sun-Drying of Fish - Safe or Dangerous for Consumers' Health? Oceanography & Fisheries 10(1) （共著） 2019/06 18. 論文　 Studies on the seasonal variation of nutritional composition and quality of Indian major carp of the old Brahmaputra river in Mymensingh district of Bangladesh THE RESEARCH SOCIETY for DIETARY HABITS 39(4),pp.219-231 （共著） 2019/05 19. 論文　 Role of IL-10 in inhibiting protective immune responses against infection with heterologous Plasmodium parasites. Parasitology International 9(70),pp.5-15 （共著） 2019/01 20. 論文　 Trend in the time of peak of the peroxide curves and TBARS curves during the ripening of pickled herring (Clupea harengus) of Britain THE RESEARCH SOCIETY for DIETARY HABITS 39(2),pp.33-46 （共著） 2019/01 21. 論文　 Metformin Promotes the Protection of Mice Infected with Plasmodium yoelii Independently of gd T Cell Expansion frontiers in Immunology 13(9) （共著） 2018/12 22. 論文　 Proximate composition, quality and flavour components of shrimp (Penaeus monodon, Penaeus orientalis, Pandalus hypsinotus). Bangladesh Journal of Fisheries 30(2),pp.263-269 （共著） 2018/12 23. 論文　 Seasonal variation in Nutritional composition and quality of two Eurasian catfish of the Old Brahmaputra river in Mymensingh district of Bangladesh. World Journal of Pharmaceutical Research 7(17),pp.1589-1601 （共著） 2018/09 24. 論文　 Differential requirements for IRF4 in the clonal expansion and homeostatic proliferation of naive and memory murine CD8+ T cells. European journal of immunology 43(8),pp.1319-1328 （共著） 2018/08 25. 論文　 Nonspecific CD8+ T Cells and Dendritic Cells/Macrophages Participate in Formation of CD8+ T Cell-Mediated Clusters against Malaria Liver-Stage Infection. Infect Immun. 86(4),e00717頁 （共著） 2018/03 26. 論文　 Modulation of immune responses by Plasmodium falciparum infection in asymptomatic children living in the endemic region of Mbita, western Kenya. Parasitol Int. 67(3),284-293頁 （共著） 2018/01 27. 論文　 THE ASSOCIATION OF RESISTANCE TO SCHISTOSOMA MANSONI REINFECTION AND HOST IMMUNITY IN MBITA KENYA COHORT AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 95(5),pp.560-561 （共著） 2017/11 28. 論文　 Activation and exhaustion of antigen-specific CD8+ T cells occur in different splenic compartments during infection with Plasmodium berghei. Parasitology International　(IF:1.860) IF合計=78.924 66(3),227-235頁 （共著） 2017/06 29. 論文　 Simple and effective method for observation of suspended parasite specimens using vaseline and paraffin mixture Parasitology International(IF:1.860) 65(5),596-598頁 （共著） 2016/10 30. 論文　 Interleukin-27-　producing CD4+ T cells regulate protective immunity during malaria parasite infection. Immunity(IF:24.082) 44(3),672-682頁 （共著） 2016/03 31. 論文　 A Proteomic Approach identifies candidate early Biomarkers to Predict Severe Dengue in Children. PLOS NEGLECTED TROPICAL DISEASES(IF:3.948) 19;10(2),e0004435頁 （共著） 2016/02 32. 論文　 Expression of PD-1/LAG-3 and cytokine production by CD4+ T cells during infection with Plasmodium parasites. Microbiology and Immunology(IF:1.428) 60(2),121-131頁 （共著） 2016/02 33. 論文　 Recruitment of distinct immune cell populations to the lung after intractracheal TLR4 signaling activation by two different stimulations. Nagasaki University School of Medicine 60(2),77-84頁 （共著） 2016/01 34. 論文　 Dynamics of Centrocestus armatus Transmission in Endemic River in Hyogo Prefecture, Japan. Tropical Medicine and Health 42(1),35-42頁 （共著） 2014/03 35. 論文　 IRF4 in Dendritic Cells Inhibits IL-12 Production and Controls Th1 Immune Responses against Leishmania major. Journal of Immunology(IF:4.985) 192(5),2271-2279頁 （共著） 2014/03 36. 論文　 Flt3 ligand treatment modulates parasitemia during infection with rodent malaria　parasites via MyD88- and IFN-–dependent mechanisms.  36(2),87-99頁 （共著） 2014/02 37. 論文　 CD8+ T cells specific for a malaria cytoplasmic antigen form clusters around infected hepatocytes and are protective at the liver stage of infection.  81(10),3825-3834頁 （共著） 2013/10 38. 論文　 Accumulation of major histocompatibility complex class II+CD11c- non-lymphoid cells in the spleen during infection with Plasmodium yoelii is lymphocyte-dependent. Microbiology and Immunology(IF:1.428) 57(3),213-223頁 （共著） 2013/03 39. 論文　 Development of memory CD8+ T cells and their recall responses during blood-stage infection with Plasmodium berghei ANKA. Journal of Immunology(IF:4.985) 189(9),4396-4404頁 （共著） 2012/11 40. 論文　 Dengue virus strain DEN2 16681 strain utilizes specific glycochain of Syndecan-2 proteoglycan as a receptor. The Journal of General Virology(IF:3.192) 93(p14),761-770頁 （共著） 2012/04 41. 論文　 Characterization of waves of leukocyterecruitment to the lung allograft and the effect of CTLA4-Ig. Nagasaki University School of Medicine 56(2),27-34頁 （共著） 2011/08 42. 論文　 Production of IFN-gamma by CD4+ T cells in response to malaria antigens is IL-2-dependent. International Immunology(IF:3.031) 22(12),941-952頁 （共著） 2010/12 43. 論文　 Interferon regulatory factor-4 differentially regulates the production of Th2 cytokine in naïve vs. effector/memory CD4+ T-cells. Proceedings of the National Academy of Sciences of the United States of America(IF:9.423) 105(41),15890-15895頁 （共著） 2008/10 44. 論文　 Malaria- specific and non- specific activation of CD8+ T-cells during infection with Plasmodium berghei. Journal of Immunology(IF:4.985) 181(2),1420-1428頁 （共著） 2008/07 45. 論文　 Development of Centrocestus armatus in different final hosts. Veterinary Parasitology(IF:2.242) 146(3-4),367-371頁 （共著） 2007/05 46. 論文　 Infection dynamics of Centrocestus armatus cercariae (Trematoda: Heterophyidae) to second intermediate fish host: survival, infectivity and transmission. The Journal of Parasitology(IF:1.394) 93(2),436-439頁 （共著） 2007/04 47. 論文　 Epidemiological study on Centrocestus armatus metacercariae in the Chikusa River, Hyogo Prefecture, Japan. Tropical Medicine and Health（学位論文） 33(1),7-11頁 （共著） 2005/03 48. 論文　 Detection of Toxoplasma oocyst from soil by modified sucrose flotation and by PCR technique. The Southeast Asian Journal of Tropical Medicine and Public Health(IF:0.773) 35(2),270-274頁 （共著） 2004/06 49. 論文　 Epidemiological survey of intestinal parasitic infections of diarrheal patients in Nepal and Lao PDR. Nepal Medical College Journal 6(1),7-12頁 （共著） 2004/06 50. 論文　 Parasites detected from diarrheal stool samples collected in Nepal. The Southeast Asian Journal of Tropical Medicine and Public Health(IF:0.773) 35(1),19-23頁 （共著） 2004/03 51. 論文　 兵庫県千種川上流域におけるCentrocestus 属（吸虫：異形吸虫科）の疫学調査　1.第一中間宿主貝における寄生状況 日本環境動物昆虫学会雑誌 14(2),97-103頁 （共著） 2003/06 52. 論文　 Detection of microorganisms in tap water in Indonesia and Thailand. Japanese Journal of Tropical Medicine and Hygiene 31(2),87-91頁 （共著） 2003/04 53. 論文　 Intestinal parasitic infections in Bekasi District, West Java, Indonesia and comparison of infection rates detected by different methods. The Southeast Asian Journal of Tropical Medicine and Public Health(IF:0.773) 33(3),462-467頁 （共著） 2002/09 54. 論文　 Differentiation of Toxocara canis and T. cati eggs by light and scanning electron microscopy. Veterinary Parasitology 92(4),287-294(Impact Factor (IF):2.242)頁 （共著） 2000/10 55. その他 FIRST AUTHOR’S   （共著） 2016/03 10件表示 全件表示(55件)

■ 所属学会 1. ～ 日本免疫学会 2. ～ 日本寄生虫学会 3. 2015/07～ ∟ 情報処理広報委員、コンサルテーション担当

■ 学歴 1. 1994/04～1998/03 大阪工業大学 工学部 応用化学科 卒業 2. 1999/04～2001/03 神戸大学大学院 医学系研究科 保健学専攻病態解析学分野 博士前期課程 博士課程修了 修士 3. 2002/04～2005/03 神戸大学大学院 医学系研究科 保健学専攻病態解析学分野 博士後期課程 博士課程修了 博士

■ 職歴 1. 2004/04～2004/08 神戸学院女子短期大学 家政科栄養コース 非常勤講師（解剖生理学実習担当） 2. 2004/09～2005/03 神戸学院大学 栄養学部栄養学科 非常勤講師（医動物学実習担当） 3. 2005/05～2007/08 長崎大学大学院 医歯薬学総合研究科感染免疫学講座免疫機能制御学分野 COE研究員 4. 2007/09～2016/04 長崎大学大学院 医歯薬学総合研究科感染免疫学講座免疫学分野 助教 5. 2016/05～ 長崎大学大学院 医歯薬学総合研究科感染免疫学講座免疫学分野 講師 6. 2018/04～ 神戸女子大学 健康福祉学部 健康スポーツ栄養学科 教授